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ADP-Glo(TM) Assay + MARK2 Kinase Enzyme System
PROVA7215
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Recombinant full-length human MARK2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. MARK2 or microtubule affinity-regulating kinase 2 is a member of the Par-1 family of serine/threonine protein kinases. MARK2 is an important regulator of cell polarity in epithelial and neuronal cells and controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. Kinase Enzyme System contains: MARK2 Kinase, 10ug (Human, recombinant full-length). MW: ~114kDa. CHKtide Substrate, 1mg/ml (KKKVSRSGLYRSPSMPENLNRPR); derived from human CDC25C protein isoform A (amino acids 205-225). 5X Reaction Buffer, 0.1M DTT.