Human Corp Water Purification System
Freephone: 0800 257 428 Email: sales@alphatech.co.nz
Recombinant full-length human MARK4 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. MARK4 or microtubule affinity-regulating kinase 4 is a member of the Par-1 family of serine/threonine protein kinases. MARK4 is predominantly expressed in the brain and readily phosphorylates Tau, MAP2 and MAP4. MARK4 co-localizes with the centrosome and microtubules in cultured cells. Overexpression of MARK4 causes thinning out of the microtubule network concomitant with the reorganization of microtubules into bundles. Kinase Enzyme System contains: MARK4 Kinase, 10ug (Human, full-length recombinant). MW: ~110kDa. CHKtide Substrate (1mg/ml) (KKKVSRSGLYRSPSMPENLNRPR); derived from human CDC25C protein isoform A (amino acid 205-225). 5X Reaction Buffer, 0.1M DTT.
