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NUAK1 Kinase Enzyme System
PROVA7252
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Recombinant full-length human NUAK1 (ARK5) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. NUAK1 or SNF1/AMP kinase-related kinase (SNARK) is a member of the NUAK family of SNF1-like kinase 1 that is also known as AMPK-related protein kinase 5 (ARK5). ARK5 is a tumor cell survival factor that is activated by AKT and acts as an ATM kinase under conditions of nutrient starvation. Kinase Enzyme System contains: NUAK1 Kinase, 10ug (Human, recombinant; full-length); MW: ~122kDa. CHKtide Substrate (1mg/ml; KKKVSRSGLYRSPSMPENLNRPR); derived from human CDC25C protein isoform A (amino acids 205-225). 5X Reaction Buffer; DTT, 0.1M.

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