Specials


NanoBRET(R) TE Selectivity DNA Controls
PRONP1000
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The NanoBRET Target Engagement (TE) K192 Kinase Selectivity System and NanoBRET TE CDK Selectivity System can quantitatively measure intracellular compound fractional occupancy against many kinases in a single experiment. These NanoBRET TE Kinase Selectivity Systems simplify cellular selectivity profiling with ready-to-use kinase-NanoLuc fusion vector panels that are transfected into HEK293 cells prior to performing the NanoBRET TE Kinase Assay. When performing the transfection step in these NanoBRET TE selectivity assays, it is recommended to include several controls that are supplied in the NanoBRET TE Selectivity DNA Controls. The preparation and use of these vector controls are detailed in Technical Manuals TM683 and TM684.