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  1. Promega
  2. Cellular & Proteomic Solutions
  3. Cell Analysis

NanoBRET(R) TE K192 Kinase Selectivity System
PRONP4050
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The NanoBRET Target Engagement (TE) K192 Kinase Selectivity System can quantitatively measure intracellular compound occupancy against a panel of 192 kinases in a single experiment. The system relies on the NanoBRET TE technology, a bioluminescence resonance energy transfer (BRET) method that uses the small, extremely bright NanoLuc luciferase as the energy donor and a cell-permeable NanoBRET TE Tracer as the energy acceptor. The K192 Kinase Selectivity System is a live-cell method using an addition-only, multiwell plate format with a single NanoBRET TE Kinase Assay. The NanoBRET TE K192 Kinase Selectivity System is optimized for each kinase to provide quantitative occupancy data, enabling cellular profiling of compound-kinase interactions.

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