Carousel pipette stand for up to 6 mechanical pipettes, except bravo
Freephone: 0800 257 428 Email: sales@alphatech.co.nz
Recombinant full-length human JNK3 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. JNK3 is a member of the c-Jun N-terminal kinases (JNKs), which are part of the mitogen-activated protein (MAP) kinase family and regulate signal transduction in response to environmental stress. JNK3 phosphorylates various transcription factors such as ATF2, Elk-1 and members of the Jun family. Activation and nuclear localization of JNK3, a neuronal-specific isoform of JNK, has been associated with hypoxic and ischemic damage of CA1 neurons in the hippocampus. Knockout mice lacking JNK3 showed reduced apoptosis of hippocampal neurons and reduced seizure induced by kainic acid, a glutamate-receptor agonist. Kinase Enzyme System contains: Kinase: JNK3, 10ug (Human, recombinant full-length). MW: ~71kDa. Substrate: p38 peptide. Other: Reaction Buffer, DTT. JNK3 NCBI Database Entry: www.ncbi.nlm.nih.gov/gene/5602/.
