Human Corp Water Purification System
Freephone: 0800 257 428 Email: sales@alphatech.co.nz
Recombinant full-length human IRAK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. IRAK1 encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. The exposure of HeLa cells or human embryonic kidney cells overexpressing IL1R to IL1 caused rapid association of IRAK with the IL1R complex and phosphorylation of IRAK. IRAK1 is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus. Kinase Enzyme System contains: IRAK1 Kinase, 10ug (Human, recombinant full-length). MW: ~132kDa. Modified AKT Substrate (1mg/ml) (modified-CKRPRAASFAE), based on the N-terminus of GSK3. 5X Reaction Buffer, 0.1M DTT.
