Human Corp Water Purification System
Freephone: 0800 257 428 Email: sales@alphatech.co.nz
Recombinant full-length human CK2 alpha 1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. CK2 alpha 1 is a serine-threonine protein kinase whose targets include many critical regulators of cellular growth. It is highly expressed in a lympho-proliferative disease of cattle and in many human cancers. Overexpression of the CK2 catalytic subunit in lymphocytes of transgenic mice leads to T cell lymphoma (1). The highest CK2 alpha 1 activity is found in mouse testicles and brain, followed by spleen, liver, lung, kidney and heart (2). Kinase Enzyme System contains: Kinase: CK2 alpha 1, 10ug (Human, recombinant full-length). MW: ~70kDa. Substrate: Native Casein Protein purified from bovine milk. Other: Reaction Buffer, DTT. CK2 alpha 1 NCBI Database Entry: www.ncbi.nlm.nih.gov/gene/1457/.
