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ADP-Glo(TM) Assay + TAOK2 Kinase Enzyme System
PROVA7305
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Recombinant human TAOK2 (amino acids 1-314) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. Thousand and one-amino acid protein kinase 2 (TAOK 2) is part of the stress-sensitive kinase cascade and activation of and binding to MKK3 by TAOK2 implicates it in the regulation of the p38-containing stress-responsive MAP kinase pathway. TAOK2 protein kinase activates p38 mitogen-activated protein kinase cascade in vitro and in cells by phosphorylating the MAP/ERK kinases MKK3 and MKK6. Kinase Enzyme System contains: TAOK2 Kinase, 10ug (Human, recombinant; amino acids 1-314). MW: ~63kDa. Native Swine Myelin Basic Protein (MBP) Substrate (1mg/ml). 5X Reaction Buffer, 0.1M DTT.