Applied Separations Solid Phase Extraction (SPE)
Freephone: 0800 257 428 Email: sales@alphatech.co.nz
Recombinant full-length human PAK7 was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag. PAK7 (also known as PAK5) is a novel human PAK family kinase that contains a CDC42/Rac1 interactive binding (CRIB) motif at the N terminus and a Ste20-like kinase domain at the C terminus. The p21-activated kinase (PAK) family of protein kinases has recently attracted considerable attention as an effector of Rho family of small G proteins and as an upstream regulator of MAPK signalling pathways during cellular events such as re-arrangement of the cytoskeleton and apoptosis. PAK7 like the other Paks has been implicated in the regulation of cell morphology, motility and transformation. Kinase Enzyme System contains: PAK7 Kinase, 10ug (Human, full-length recombinant). MW: ~130kDa. Akt Peptide substrate (1mg/ml), (CKRPRAASFAE); derived from N terminus of GSK3. 5X Reaction Buffer, 0.1M DTT.
