Specials


ADP-Glo(TM) Assay + EIF2AK1 (HRI) Kinase Enzyme System
PROVA7134
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Recombinant full-length human EIF2AK1 (HRI) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. EIF2AK1 (HRI) or eukaryotic translation initiation factor 2-alpha kinase 1 acts at the level of translation initiation to downregulate protein synthesis in response to stress. EIF2AK1 (HRI) is a kinase that can be inactivated by hemin and is activated by heme deficiency and other stimuli and is a major protein kinase that phosphorylates EIF2-alpha. Kinase Enzyme System contains: EIF2AK1 (HRI) Kinase, 10ug (Human, recombinant; full-length). MW: ~120kDa. RS Repeat Peptide (1mg/ml), (GRSRSRSRSRSRSRSR). 5X Reaction Buffer, 0.1M DTT.