CyBio Drop automated liquid handler
Freephone: 0800 257 428 Email: sales@alphatech.co.nz
The RANKL Bioassay is a bioluminescent cell-based assay designed to measure RANK/RANKL pathway stimulation or inhibition. The RANKL Bioassay Cells are provided in a thaw-and-use format as cryopreserved cells that can be thawed, plated and used in an assay without the need for cell propagation. The RANKL Bioassay is also available in a Cell Propagation Model (CPM) format, which includes cryopreserved cells that can be thawed, propagated, and banked for long-term use (RANKL Bioassay, Propagation Model, Cat.# J3102). The RANKL Bioassay is comprised of a human cell line engineered to express the RANK receptor and a luciferase reporter driven by a response element (RE). When RANKL binds the RANK receptor, transduced intracellular signals activate the RE, resulting in luminescence.
