Specials

Recombinant full-length human p38 gamma was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. p38 gamma is a member of the p38 MAPK family, which is activated in response to stress. p38 gamma gene was mapped to 22q13.3 and functions as a signal transducer during differentiation of myoblasts to myotubes. Enforced localization of p38 gamma in the nucleus or cytoplasm markedly attenuates the ability of the kinase to induce cell cycle arrest in fibroblasts. p38 gamma increases basal glucose uptake and decreases DNP- and contraction-stimulated glucose uptake, partially by affecting levels of glucose transporter expression in skeletal muscle. Kinase Enzyme System contains: Kinase: p38 gamma, 10ug (Human, recombinant full-length). MW: ~71kDa. Substrate: p38 peptide. Other: Reaction Buffer, DTT. p38 gamma NCBI Database Entry: www.ncbi.nlm.nih.gov/gene/6300/.