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MSK2 Kinase Enzyme System
PROV5080
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Recombinant full-length mouse MSK2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. MSK2 or mitogen- and stress-activated protein kinase-2 is a member of the serine/threonine kinases family that contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and c-fos. MSK2 is also known as ribosomal protein S6 kinase 4 (RPS6KA4) that is activated by the mitogen-activated protein kinases ERK1, ERK2 and p38. Kinase Enzyme System contains: Kinase: MSK2, 10microg (Mouse, recombinant full-length). MW: ~114kDa. Substrate: RSK Substrate (KRRRLSSLRA); derived from human 40S ribosomal protein S6 (amino acid 230-239). Other: Reaction Buffer, DTT. MSK2 NCBI Database Entry: www.ncbi.nlm.nih.gov/gene/56613/.

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