Human Corp Water Purification System
Freephone: 0800 257 428 Email: sales@alphatech.co.nz
Recombinant human MRCKalpha (1-473) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. Myotonic Dystrophy Kinase-Related Cdc42-Binding Kinase ? (MRCK?) is a Cdc42/Rac/Rho interactive/binding serine/threonine kinase with multiple functional domains. MRCKs are effectors of RhoA and Cdc42, respectively, for actin reorganization. MRCK? is a critical regulator of signal transduction pathways in eukaryotic cells that are known principally for their role in regulating the cytoskeleton, and they do so by recruiting a variety of downstream effector proteins. Kinase Enzyme System contains: Kinase: MRCK?, 10microg (Human, recombinant; amino acids 1-473). MW: ~73kDa. Substrate: S6K substrate (KRRRLASLR); derived from human 40S ribosomal protein S6 (amino acid 230-238). Other: Reaction Buffer, DTT. MRCK? NCBI Database Entry: www.ncbi.nlm.nih.gov/gene/8476/.
