Specials

Recombinant human MAPKAPK2 (46-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag. MAPKAPK2 (MAPKAP kinase2) is a Ser/Thr protein kinase that is regulated via direct phosphorylation by p38 MAP kinase (1). In conjunction with p38 MAP kinase, MAPKAPK2 is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 has been shown to be one of the substrates of MAPKAPK2, in vivo. Kinase Enzyme System contains: Kinase: MAPKAPK2, 10ug (Human, recombinant; amino acids 46-end). MW: ~41kDa. Substrate: HSP27tide (RRLNRQLSVA-amide); derived from the mouse HSP27 (amino acids 80-85). Other: Reaction Buffer, DTT. MAPKAPK2 NCBI Database Entry: www.ncbi.nlm.nih.gov/gene/9261/.