Bioneer ExiProgen EC1 Protein Synthesis Kit (automated)

Endoproteinase Lys-C is a serine protease isolated from Lysobacter enzymogenes as a highly purified protease that hydrolyzes specifically at the carboxyl side of Lys. Lys-C retains proteolytic activity under protein denaturing conditions such as 8M urea, which is used to improve digestion of proteolytically resistant proteins. Lys-C activity is optimal in the pH range of 7.0-9.0. This protease can be used alone or in combination with other proteases to produce protein digests for peptide mapping applications or protein identification by peptide mass fingerprinting or MS/MS spectral matching.