Specials

Recombinant full-length human DGKQ was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. Diacylglycerol kinase theta (DAG kinase theta) is the only member of class V diacylglycerol kinase, which contains three cysteine-rich domains, a proline-rich region, and a Ras-associating domain and mediates the regeneration of phosphatidylinositol from diacylglycerol in cell signal transduction. DGKQ has been associated with Parkinson?s disease in a genome-wide meta-analysis study. Stimulated DGK theta activity promotes the SF1-dependent transcription of CYP17 in human adrenocortical cells. Kinase Enzyme System contains: DGKQ Kinase, 10ug (Human, recombinant, full-length);. MW: ~130kDa. Dilauroyl-sn-glycerol Substrate, 10mM. 5X Reaction Buffer; DTT, 0.1M; Lipid Dilution Buffer II.