Gyrozen universal clinical centrifure
Freephone: 0800 257 428 Email: sales@alphatech.co.nz
The CD40 Bioassay is a bioluminescent cell-based assay for measuring the potency and stability of ligands or agonist antibodies and other biologics that can bind and activate CD40. The CD40 Bioassay reflects the mechanism of action (MOA) of biologics designed to activate the CD40 receptor. Specifically, CD40-mediated luminescence is detected following the addition of CD40 agonist antibodies or CD40 ligand. The bioassay is prequalified according to ICH guidelines and shows the precision, accuracy and linearity required for routine use in potency and stability studies. Control Ab, Anti-CD40, is a mouse anti-human CD40 agonist antibody. It can be used as a positive control in the CD40 Bioassay in the presence of Fc?RIIb CHO-K1 Cells (Cat.# J2232, JA2251, JA2255).
