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ADP-Glo(TM) Assay + TIE2 (Y897S) Kinase Enzyme System
PROVA7317
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Recombinant human TIE2 (Y897S) (amino acids 771-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. TIE2 or TEK is a receptor tyrosine kinase that is expressed principally on vascular endothelium. Disrupting TIE2 function in mice results in embryonic lethality with defects in embryonic vasculature, suggests a role in blood vessel maturation and maintenance. Kinase Enzyme System contains: TIE2 (Y897S) Kinase, 10ug (Human, recombinant; amino acids 771-end). MW: ~65kDa. Poly (4:1 Glu, Tyr) Substrate (1mg/ml). 5X Reaction Buffer, 2.5M MnCl2, 0.1M DTT.