Human Corp Water Purification System
Freephone: 0800 257 428 Email: sales@alphatech.co.nz
Recombinant human MET (Y1230C) (amino acids 956-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. MET is a proto-oncogene that encodes a transmembrane growth factor receptor, which is a heterodimer of two disulphide-linked chains of 50kDa (alpha) and 145kDa (beta). MET is widely expressed in the kidney, brain, lung, skin and embryonic tissue. Hepatocyte growth factor (HGF) binds to MET and activates its tyrosine kinase activity. MET is overexpressed and activated in a variety of human cancers including pancreatic, colon, gastric, cervical and ovarian and has been shown to be involved in tumor cell migration and invasion. Kinase Enzyme System contains: MET (Y1230C) Kinase, 10ug (Human, recombinant; amino acids 956-end). MW: ~81kDa. Poly (Glu4, Tyr1) Substrate (1mg/ml). 5X Reaction Buffer, 2.5M MnCl2, 0.1M DTT.
