CyBio Drop automated liquid handler
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Recombinant human EPHB4 (amino acids 561-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. EPHB4 is a member of the Eph family of receptor tyrosine kinases which play a role in regulating cell adhesion and cell movement during embryonic development. Furthermore, because tissue disorganization and abnormal cell adhesion, movement, and survival characterize the more advanced stages of cancer, the inappropriate functioning of Eph receptor could play a causal role in malignancy. EPHB4 is uniquely expressed in the vascular endothelial and endocardial cells and animal knockout studies with EPHB4 reveal a phenotype that is similar to Ephrin B2 gene knockdown. Kinase Enzyme System contains: EPHB4 Kinase, 10ug (Human, recombinant; amino acids 561-end). MW: ~72kDa. Poly (Glu4, Tyr1) Peptide Substrate (1mg/ml). 5X Reaction Buffer, 2.5M MnCl2, 0.1M DTT.
