The colours of pharmaceutical powders, such as sorbitol, microcrystalline cellulose or dibasic calcium phosphate anhydrous, are often measured as an incoming QC check to ensure lot-to-lot consistency. The preferred method for measuring powders is to use a Directional 45°/0° reflectance geometry for its ability to measure colour the way the human eye sees colour. This is the geometry that is recommended by HunterLab for colour measurement of opaque materials that will be viewed by the customer.
In many cases, mixtures of finely divided drugs that are eventually made into capsules, caplets, creams and other forms of medicines are pressed into plaques for the purpose of coluor measurement prior to final processing to ensure lot-to-lot and batch-to-batch colour consistency.
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