Specials

BioTools Protein Analysers
BIOPROTEIN
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FT-IR Spectroscopy of Biologics

BioIR™ is a family of dedicated solutions for the biopharmaceutical industry based on FT-IR instrumentation and comprised of specialized software and databases. The first such system, PROTA™, was introduced in 1998 and has since rapidly become the industry’s preferred choice. PROTA™ provides a fast, cost-effective and sensitive way to determine secondary structure of a protein or to follow structural changes due to perturbations. This turnkey system is designed to be used by both spectroscopists and non-spectroscopists. It’s user-friendly, intuitive software guides users through data acquisition and analysis. PROTA™ includes all of the functions, in one integrated package, required to link IR spectral data and protein structure.

Applications

Formulation studies (liquids and solids) - effects of excipients, pH and buffers
Determination of secondary structures of de novo proteins
Conformational stability and dynamics
Structure in aggregates
Mutation studies
Structural characterization upon environmental effects
Stability studies (thermal and chemical)
Drug delivery
Protein-protein, protein-DNA/RNA and protein-drug interactions
Crystallization condition screening